A Systematic Review of the European Rapid Alert System for Food and Feed: Tendencies in Illegal Food Supplements for Weight Loss

Background : Slimming products represent a dynamically growing group of food supplements worldwide. The efficacy safely usable natural ingredients is usually below consumers’ expectations. Certain manufacturers add unauthorized or prohibited to weight loss in order increase their efficacy. Hence, many these are adulterated and may pose risk the health. Aims aim our work was give an overview on used slimming products, summarize frequently synthetic adulterants also assess trends illegal European Union based warnings Rapid Alert System for Food Feed (RASFF) time period 1988–2019. Methods Reports between 1988–2019 were extracted from RASFF portal January 1, 2020. Each entry individually reviewed. Results 2,559 records with quality problems identified RASFF, several which [319 (12,5%)] marketed facilitate loss. 202 (63,3%) contained unapproved, drug ingredients. major adulterant (113 319, 35.4%) DNP (2,4-dinitrophenol), whereas sibutramine second most frequent agent (69 21,6%) 1988 2019. Conclusion number approved medicines indication relatively low (and that ingredients) limited. Therefore, significant satisfy patients’ cause serious adverse effects sensitive patients.